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Editorial
In This Issue
Quentin Rae-Grant
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Original Research
Quality of Life in OCD: Differential Impact of Obsessions, Compulsions, and Depression Comorbidity

Mario Masellis, Neil A Rector, Margaret A Richter

(PDF)

A Pilot Study of a Parent-Education Group for Families Affected by Depression
Mark Sanford, Carolyn Byrne, Susan Williams, Sandy Atley, Ted Ridley, Jennifer Miller, Heather Allin

(PDF)

Differentiating Symptoms of Complicated Grief and Depression Among Psychiatric Outpatients
John S Ogrodniczuk, William E Piper, Anthony S Joyce, Rene Weideman, Mary McCallum, Hassan F Azim, John S Rosie

(PDF)

Filicidal Women: Jail or Psychiatric Ward?
Line Laporte, Bernard Poulin, Jacques Marleau, Renée Roy, Thierry Webanck

(PDF)

Phenomenology and Comorbidity of Dysthymic Disorder in 100 Consecutively Referred Children and Adolescents: Beyond DSM-IV
Gabriele Masi, Stefania Millepiedi, Maria Mucci, Rosa Rita Pascale, Giulio Perugi, Hagop S Akiskal

(PDF)

A Multicentre Prospective Controlled Study to Determine the Safety of Trazodone and Nefazodone Use During Pregnancy
Adrienne Einarson, Lori Bonari, Sharon Voyer-Lavigne, Antonio Addis, Doreen Matsui, Yvette Johnson, Gideon Koren

(PDF)


Brief Communication
Clozapine Treatment in Patients With Prior Substance Abuse

Deanna L Kelly, Elizabeth A Gale, Robert R Conley

(PDF)

The Effect of Peer Support on Postpartum Depression: A Pilot Randomized Controlled Trial
Cindy-Lee Dennis

(PDF)


Book Reviews
(PDF)

Psychological Aspects of Women’s Health Care: The Interface Between Psychiatry and Obstetrics and Gynecology. 2nd Edition.
Reviewed by
Vera Lantos, MD, FRCPC

Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques.
Reviewed by
Jimmy Jensen, PhD,
Shitij Kapur, MD, FRCPC, PhD

Planification et évaluation des besoins en santé mentale.
Revue par
Raymond Tempier, MD

Clinical Interaction and the Analysis of Meaning: A New Psychoanalytic Theory.
Reviewed by
Paul Ian Steinberg, MD, FRCPC

Evidence and Experience in Psychiatry. Volume 2: Schizophrenia.
Reviewed by
Mary V Seeman, MD

Schizophrenia Revealed: From Neurons to Social Interactions.
Reviewed by
Emmanuel Stip, MD

How’s Your Marriage? A Book for Men and Women.
Reviewed by
Karl M Tomm, MD FRCPC,
Cynthia A Beck, MD MASc FRCPC

L’extermination des malades mentaux dans l’allemagne nazie.
Revue par
Frédéric Grunberg, MD

Physicalism and Its Discontents.
Reviewed by
Dorian Deshauer, MD FRCP


Letters to the Editor
(PDF)

Zenker’s Diverticulum and Psychosis in the Elderly

Anorgasmia and Withdrawal Syndrome in a Woman Taking Gabapentin

Stage-Oriented Trauma Treatment Using Dialectical Behaviour Therapy

Sexual Sadism With Lust-Murder Proclivities in a Female?

Topiramate-Induced Suicidality

Bright-Light Therapy in Somatization Disorder

Venlafaxine-Induced Delirium

New Dosage-Reduction Regime to Avoid Paroxetine Discontinuation Syndrome

Risperidone-Induced Galactorrhoea: A Case Series

Gamma Hydroxybutyrate Withdrawal in an Orthopedic Trauma Patient

Version française de la Wender Utah Rating Scale (WURS)

Original Research

A Pilot Study of a Parent-Education Group for Families Affected by Depression

Mark Sanford, MBChB, FRCPC1, Carolyn Byrne, PhD2, Susan Williams, PhD, CPsych3, Sandy Atley, RN, BScN4, Ted Ridley, BA5, Jennifer Miller, RN, BScN5, Heather Allin, BSc7

 

Objective: This study assessed the feasibility and efficacy of a parent-education group for families with young children and a parent with depression. We designed the program to be readily disseminated if shown to be effective.

Method: We recruited 44 parents with depression from clinics and family doctors in Hamilton, Ontario, and randomly assigned them to receive the parenting program or to a wait-list control group. The outcomes measured included knowledge of depression, parenting, family relationships, depression symptoms, child depressive symptoms, and functioning. We used analysis of covariance to test for posttreatment differences between experimental and control groups.

Results: Of the treatment group, 27% dropped out at posttreatment, and 43% by follow-up. Those who dropped out had more severe depression at baseline than did those who completed the program, and there was selective loss of parents with more severe depression in the experimental group. In intention-to-treat analyses at posttreatment, probands in the experimental group reported more improvements on family functioning, parenting sense of competence, and family and parent conflict than did control subjects. Standardized effect sizes (ES) were medium (0.4 to 0.6). When baseline depressive symptom scores were controlled in the analyses, the between-group differences were reduced, showing that selective loss of participants may have influenced the findings.

Conclusions: On balance, the results are encouraging and support the further development and evaluation of the group intervention. However, the study does not provide unequivocal evidence in support of the program. Before it is transferred to other settings, the program needs further modification to improve participation by parents with more severe depression and further evaluation of its effectiveness.

(Can J Psychiatry 2003;48:78–86)

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Clinical Implications

  • If further evaluation confirms that this parent-education group program reduces family dysfunction and improves parenting and child outcomes, it will a be useful adjunctive preventive intervention for families affected by depression.

Limitations

  • Small sample size and measurement weaknesses reduced opportunities for hypothesis testing and consideration of the findings’ clinical significance.

  • As is commonly seen in targeted preventive interventions, parents with more severe depression are less likely to participate, although they may be able to do so once their depression has lifted.


Key Words
: parental depression, parenting, randomized controlled trial, prevention, child maladjustment

Résumé : Une étude pilote d’un groupe d’éducation des parents pour les familles touchées par la dépression

Children of parents with depression are at high risk for various negative outcomes, including major depressive disorder (MDD) (with an approximately 40% cumulative risk for MDD by age 20 years) and other emotional and behavioural disorders (1–3). One study also reports high suicide rates and poor home and school functioning (4). Families with marital discord, parenting problems, and chronic and severe parental affective illness are at greatest risk for negative outcomes (3,5). Further, parental depression is associated with other risk factors for child maladjustment (for example, financial hardship, parental unemployment, and marital discord) and with lowered social support (6,7). While these associations are well documented, the causal mechanisms involving genes, child cognition, and environmental factors are just beginning to be elucidated (8,9).

Parental depression also negatively influences parent–child relationships, leading to insecure attachment in young children, reduced maternal responsiveness, reduced sensitivity to interactions initiated by infants, reduced overall maternal–infant interactions, and a more negative relationship tone (10,11). These interactional patterns are bidirectional. For instance, mothers with depression and their infants matched negative behavioural states more often and positive behavioural states less often than did dyads without depression (12), and mothers with depression behaved differently toward symptomatic children than toward their nonsymptomatic siblings (13). Overall, the findings suggest that negative interactional patterns arising in parent–child dyads are key to the development of child problems in families with a parent suffering from depression. Further study is needed to document specific maladaptive patterns and to evaluate interventions targeted at these maladaptive interactions.

Earlier work with affected families showed that child disturbance increases with the child’s increasing age (3). Therefore, prevention strategies directed at children should be most efficient if they target older children and adolescents. A recent trial, for example, tested the preventive effects of cognitive therapy in symptomatic (but not showing a disorder) adolescent offspring of parents with depression. Adolescents receiving the group intervention were significantly less likely to experience a depressive episode over 12-month follow-up (9.3% and 28.8% in the experimental group and usual-treatment control subjects, respectively) (14). However, it is also appropriate to target families with infants, preschool, and preadolescent children. The most extensive study to date compared family psychoeducation with a didactic presentation. After 18 months, those receiving the family program were functioning significantly better than those randomized to the lecture series (15). At 3-year follow-up, the family intervention led to improved family communication, less parental guilt, better understanding of the parent’s illness by the child, fewer depressive symptoms, and better child adaptive functioning (16). The program was designed to treat a single family at a time and was implemented by experienced clinicians. Perhaps owing to these factors, it has not been widely disseminated.

We have developed a group program targeted at parents with depression and their partners. The aim is to increase knowledge about depression’s effect on the family and to enhance family functioning, thereby reducing risk to the children. The program is structured, manualized, and designed to be administered by clinicians without a high level of psychotherapeutic expertise. Thus, it should be easily transferable to other settings if shown to be effective. At this stage, there is no direct child involvement, although this would be a necessary component of any comprehensive program addressing the varied needs of affected families. This pilot study assessed the intervention’s feasibility and acceptability and obtained preliminary evidence of its effectiveness in enhancing parental knowledge and functioning.

Description of the Intervention

The program is based on family psychoeducation and parent-training models. Family psychoeducation was developed to provide information and to foster communication, as well as family problem-solving and coping skills, in families with a member affected by schizophrenia (17,18). The parent-training model was developed specifically for families with children suffering from behaviour disorders. It incorporates concepts and methods derived from social-learning theory (specifically, coping-modelling procedures), parent-education theory (specifically, cognitive strategies and contingency-management techniques), and family-systems theory (specifically, family problem solving, collaborative approaches to management, and supportive communication) (19). The group program borrowed from each of these models with the aims of increasing the parents’ knowledge about depression and its impact on the family, of increasing spousal support, of increasing positive communication, and of enhancing positive parenting strategies directed at child problems common to these families. The program comprised 8 weekly, 2-hour sessions with 8 to 12 parent participants (alone or with their partner or a family member). The sessions included a socialization opportunity, a review of minutes from the previous session, didactic information sharing, viewing and group critique of video analogues portraying difficult parenting situations, the group leader’s summary of the session, and a group discussion to set a homework task. Each session focused on a specific issue confronting families with a parent suffering from depression (for example, a child’s withdrawal from peers) and on parenting strategies relevant to the issue. Free on-site child care was provided to facilitate the attendance of parents with young children.

There is overlap with the previously evaluated family program (15), but the intervention also differs in important ways. It is a parent-group intervention, and children are not present. The focus is broader, in that general communication and problem-solving methods are covered along with the enhancement of specific parenting strategies, with an emphasis on understanding and reversing depression’s negative impact on parenting. The rationale is that improved parenting will strengthen parent–child relationships over the longer term and reduce negative child outcomes.

Study Design and Hypotheses

The pilot study was a controlled trial with participants randomized to the parent group or to a wait-list control group. The main outcomes, measured posttreatment and at 3-month follow-up, were knowledge of depression, parenting practices, sense of parenting competence, family relationships and functioning, and depressive symptoms. Secondary outcomes concerned child functioning. The goal was to assess whether participation in the experimental group led to immediate positive changes in targeted areas of family functioning. Because the study was exploratory, rather than confirmatory, we did not test specific hypotheses. However, a priori, preliminary evidence of effectiveness was taken to be demonstrated if the experimental group scored higher at posttreatment and follow-up on knowledge of depression, parenting, and family relationship measures, with standardized ES > 0.5.

Methods

Participants
We recruited participants from adult psychiatry services and family doctors in Hamilton-Wentworth, Ontario. In addition, we posted flyers describing the study in clinics and public areas. Individuals who contacted the study coordinator directly were asked to seek a referral from their doctor. We required the parent proband to have a clinical diagnosis of MDD according to the referring physician, to be currently under medical care for depression, and to have a child aged 6 through 13 years. One child in this age range was selected, and all child-related measures involved ratings for the selected child. The study coordinator selected the study child to ensure a good balance of age and sex in the sample, but without knowledge of the child, apart from age and sex. We excluded parents who were currently suffering from mania or psychosis or who were judged to be acutely suicidal or unable to participate in a group.

Table 1 provides baseline descriptive statistics. The proband mean age was 41 years, and there were more women than men (only 4 men were included as probands). A sizeable minority were single parents (33%). Most probands in both groups had postsecondary education and were working full- or part-time. Partners reported higher rates of postsecondary education, and almost all were employed full-time. Although all probands met the inclusion criteria (MDD in the past 12 months, according to the referring clinician), not all met DSM-IV MDD criteria as assessed by the Composite International Diagnostic Interview (CIDI) (76% and 83% in experimental and control groups, respectively). Of the partners, 7 (25%) met MDD criteria, based on the CIDI interview. Among probands, the mean Centre for Epidemiologic Studies-Depression (CES-D) self-report score was above the recommended clinical cutoff (> 16), the mean number of lifetime MDD episodes was 7, and the mean number of previous psychiatric hospitalizations was 3. Almost all the probands (95%) were currently receiving medication for depression, and most were seeing a psychiatrist or family doctor. Probands with depression described more depressive symptoms in the index child than did their partner and child. Overall, these statistics describe a sample with moderate-to-severe depressive disorders.

Table 1  Sociodemographic and clinical characteristics of the sample

Characteristic

Experimental group (n = 21)

Control group
(n = 23)

Proband age (years), Mean (SD)

Study child age (years), Mean (SD)

Number of siblings, Mean (SD)

 

Sex of proband female, n (%)

Single parent family, n (%)

Family income $20 000 or less, n (%)

Receives social support, n (%)

Socioeconomic status

      Upper-middle, n (%)

      Middle, n (%)

      Lower-middle, n (%)

41.3  (6.0)

10.6  (2.5)

1.5  (1.2)

 

19  (90)

7  (33)

5  (24)

4  (19)

3  (15)

11  (55)

6  (30)

40.8 (6.8)

9.7 (2.7)

1.1 (0.8)

21 (91)

7 (33)

6 (29)

3 (13)

9  (39)

10  (44)

4  (17)

 

Proband (n = 21)

Partner  (n = 14)

Proband  (n = 23)

Partner (n = 14)

Some postsecondary education, n (%)

Employed

      Full-time, n (%)

      Part-time, n (%)

      Neither, n (%)

MDD by CIDI past 12 months, n (%)

CES-D score, Mean (SD)

12 (57)

     

7 (35)

6 (30)

7 (35)

16 (76)

30.1 (13.7) 

12 (86)

12 (100)

3 (14)

11.5 (14.4)

18 (78)

7 (35)

5 (25)

8 (40)

19 (86)

     33.2 (14.0)          

10 (71)

13 (93)

1 (7)

4 (28)

12.5 (9.5)

MDD episodes (life), Mean (SD)

Psychiatric hospitalization (ever), n (%)

Number of hospitalizations, Mean (SD)

Currently on antidepressants, n (%)

Currently treated, n (%)

      Family doctor, n (%)

      Psychiatrist, n (%)

      Family included in treatment, n (%)

CDI scores

      Child informant, Mean (SD)

      Proband informant, Mean (SD)

      Partner informant, Mean (SD)

7.8  (5.1)

10  (48)

3.5 (2.5)

19 (95)

20 (95)

9 (43)

13 (62)

10 (48)

            

9.4 (8.6)

11.7 (8.7)

8.5 (6.3)

7.6 (7.6)

10 (23)

2.0 (1.1)

22 (96)

23 (100)

16 (70)

12 (52)

11 (48)

              

8.0 (7.2)

11.1 (6.9)

6.6 (4.8)

CDI = Children’s Depression Inventory; CIDI = Composite International Diagnostic Interview; CES-D = Centre for Epidemiology Studies-Depression scale; MDD = major depressive disorder


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