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Editorial
Challenges at the Pharmaceutical–Physician Boundary
Quentin Rae-Grant
(PDF)

Guest Editorial
Suicide: The Persisting Challenge
Isaac Sakinofsky
(PDF)


In Review
The Neurobiology of Suicide and Suicidality

Kees van Heeringen

(PDF)

Assessing Suicidal Youth With Antisocial, Borderline, or Narcissistic Personality Disorder
Paul S Links, Brent Gould, Ruwan Ratnayake

(PDF)


Original Research
Sexsomnia — A New Parasomnia?

Colin M Shapiro, Nikola N Trajanovic, J Paul Fedoroff

(PDF)

A Case–Control Study on Psychological Symptoms in Sleep Apnea-Hypopnea Syndrome
Weihua Yue, Wei Hao, Pozi Liu, Tieqiao Liu, Ming Ni, Qi Guo

(PDF)

Suicide Attempts in Turkey: Results of the WHO–EURO Multicentre Study on Suicidal Behaviour
Halise Devrimci-Ozguven, Is1k Say1l

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Review Paper
Adverse Effects Associated With Physical Restraint

Wanda K Mohr, Theodore A Petti, Brian D Mohr

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Brief Communication
Insight and Neuropsychological Function in Patients With Schizophrenia and Bipolar Disorder With Psychotic Features

Luca Arduini, Artemis Kalyvoka, Paolo Stratta, Osvaldo Rinaldi, Enrico Daneluzzo, Alessandro Rossi

(PDF)

Time of Day Influences Nonattendance at Urgent Short-Term Mental Health Unit in Victoria, British Columbia
Rivian Weinerman, Vi Glossop, Randy Wong, Lara Robinson, Karen White, Rif Kamil

(PDF)

Diabetes Mellitus and Impaired Glucose Tolerance in Patients With Schizophrenia
Mythily Subramaniam, Siow-Ann Chong, Elaine Pek

(PDF)


Book Reviews
(PDF)

Language Impairment and Psychopathology in Infants, Children and Adolescents.
Reviewed by
JH Beitchman, MD

Women’s Mental Health: A Comprehensive Textbook.
Reviewed by
Gail Erlick Robinson, MD, DPsych, FRCPC

Psychiatric and Cognitive Disorders in Parkinson’s Disease.
Reviewed by
Erwin K Koranyi, MD

Un jour la santé.
Reviewed by
Paul Beaudry, MD, FRCP

Seeking Safety: A Treatment Manual for Posttraumatic Stress Disorder and Substance Abuse.
Reviewed by
George A Fraser, MD

Treatment-Resistant Mood Disorders.
Reviewed by
Sagar V Parikh, MD, FRCPC


Letters to the Editor
(PDF)

QTc Prolongation: Chlorpromazine and High-Dosage Olanzapine

Should Lipids be Monitored During the First Year of Treatment with an Atypical Antipsychotic?

Quetiapine May Induce Mania: A Case Report

Insight, Knowledge, and Beliefs About Illness in First-Episode Psychosis

The Symptoms of Atypical Depression

Potential Risk of Diabetes Mellitus With the Use of Atypical Antipsychotic Medication

Clozapine-Induced Aplastic Anemia in a Patient With Parkinson’s Disease

Early-Onset Obsessive–Compulsive Disorder

Treatment Noncompliance With Orally Disintegrating Olanzapine Tablets

Letters to the Editor

Early-Onset Obsessive–Compulsive Disorder

Dear Editor:

Studies have reported high prevalence rates (6-month prevalence of 0.5% to 1%) of obsessive–compulsive disorder (OCD) in children and adolescents (1). Although the childhood onset-age of OCD in most clinical samples has ranged from age 6 to 11 years (2), the disorder has been found in children as young as age 3 years. We report the case of patient with early-onset OCD who presented for psychiatric consultation many years after the onset of illness.

Case Report

Mr A, age 16 years, is a slow-to-warm-up high-school student from a middle socioeconomic background. He presented for the first time to the clinic with a 2½-year history of school refusal and irritability. On clarification, it was apparent that from a very young age (even before age 5 years) he was excessively concerned about dirt. He would avoid looking at the toilet, even while using it, take an abnormally long time washing his face (his clothes getting wet in the process) and bathing, and would not allow anyone to use his towels. He would also avoid using toilets outside his own house whenever he went on a trip. About 2½ years before presenting to the clinic, he also began to have obsessive images of a dirty bathroom and toilet. Further, he began to fear that he would forget lessons studied and, hence, fail to answer either in class or during examinations. Consequently, he avoided exams and refused to go to school. He also thought that people were talking about him on the road and had checking compulsions yielding to these obsessive doubts, fears that books given to friends might get lost, compulsive reassurance seeking, repeated intrusive ruminations about events during the day, and thoughts that he would be responsible for something bad happening. He was also found to have a history suggesting separation anxiety disorder of childhood, sibling rivalry, and oppositional tendencies, for which psychiatric consultation had not been sought. The family history suggested unspecified mental illness in his maternal grand-aunt and maternal uncle, possible depressive illness in his paternal great-grandmother, and subclinical obsessive–compulsive symptoms in his mother’s maternal uncle. Although he had poor insight and was uncooperative for treatment at the time of presentation, he started showing response to sertraline (up to 150 mg daily). Later, he started cooperating with exposure- and response-prevention therapy for his contamination obsessions and with audioexposure therapy for his obsessive fear of forgetting lessons learned. At the end of 4 weeks’ inpatient treatment, his obsessions and compulsions showed significant improvement.

This case highlights the fact that OCD may have onset at a very early age and is in keeping with the earlier findings of early onset being associated with male sex and positive family history (3). The long time-lag before this case actually presented to a psychiatrist indicates the need for increased awareness among professionals, especially because the illness arises at a developmentally important period.

References

1. Zohar A. The epidemiology of obsessive compulsive disorder in children and adolescents. Psychiatr Clin North Am 1999;8:445.

2. Piacentini J, Graae F. Childhood obsessive–compulsive disorder. In: Hollander E, Stein DJ, editors. Obsessive–compulsive disorders: etiology, diagnosis, and treatment. New York: Marcel Dekker; 1997. p 23.

3. Swedo S, Rapoport J, Leonard H, Lenane M, Cheslow D. Obsessive–compulsive disorder in children and adolescents: clinical phenomenology of 70 consecutive cases. Arch Gen Psychiatry 1989;46:335.

Dr Sagnik Bhattacharyya, DPM, DNB, MD; Dr Girishchandra BG, DPM, DNB;
Dr Sumant Khanna, MD, MNAMS, MRCPsych, PhD
Bangalore, India




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