May 1996, Volume 41, Number 4


A Critical Review of Recovered Memories in Psychotherapy: Part I -- Trauma and Memory

Joel Paris, MD

Objective:

The theoretical basis of the use of recovered memories in psychotherapy will be critically examined.

Method:

Literature will be reviewed on the nature of normal memory, and on the relationship of trauma to memory.

Results:

Normal memories are surprisingly inaccurate. There is little evidence that normal memories can be repressed. There is no evidence that trauma makes repression more likely.

Conclusions:

"Recovery" of repressed memories is not consistent with the findings of empirical research.

(Can J Psychiatry 1996;41:201-205)

Key Words:

trauma, memory, psychotherapy


A Critical Review of Recovered Memories in Psychotherapy: Part II --Trauma and Therapy

Joel Paris, MD

Objective:

The clinical implications of the use of recovered memories in psychotherapy will be examined.

Method:

The paper will review the relationship of trauma to psychopathology and discuss how traumatic histories might be dealt with in therapy.

Results:

Trauma is a risk factor for psychopathology, but is only one of many etiological factors in mental disorders. The search for recovered memories in psychotherapy could present dangers for patients.

Conclusions:

The most reliable memories of trauma are those that have been present throughout the patient's life.

(Can J Psychiatry 1996;41:206-210)

Key Words:

trauma, memory, psychotherapy


The Characteristics and Intervention Histories of Incarcerated and Conduct-Disordered Youth

Jalal Shamsie, MB, FRCPC, Hayley Hamilton, MA, and Cynthia Sykes, MPhil

Objectives:

1) To determine if incarcerated youth and conduct-disordered youth in treatment display similar risk factors associated with chronicity of antisocial behaviour; 2) to determine if incarcerated youth had experienced high numbers of interventions by many different agencies as has been reported for conduct-disordered youth in treatment.

Method:

The files of 25 conduct-disordered youth in treatment and 25 incarcerated youth were examined to extract all relevant data.

Results:

Incarcerated youth were similar to conduct-disordered youth with regard to the number of symptoms of disruptive behaviour disorders, age of onset of behavioural problems, and family backgrounds. Both groups had high numbers of interventions and agencies in their histories. Interventions began earlier for the conduct-disordered youth.

Conclusion:

The distinction between conduct-disordered youth who are treated and youth who are incarcerated may be arbitrary and accidental. Given the similarity in the clinical characteristics, incarcerated youth should be offered help that is similar to that offered to conduct-disordered youth. Such help may lower the rate of recidivism.

(Can J Psychiatry 1996;41:211-216)

Key Words:

conduct disorder, treatment, posttreatment follow-up, continuum of care, early identification


Suicide in Old Age: A Tragedy of Neglect

Geoffrey Duckworth, MD, PhD, Dip, Psych, FRCPC, Hazel McBride BA, BEd, MA, PhD, OTC

Objective:

To investigate the incidence and treatment of depression in geriatric suicide.

Method:

All coroners' records, autopsy and police reports for suicide victims aged 65+ in Ontario (n = 543) over 3 years were examined.

Results:

Over 80% of the elderly who committed suicide received no psychiatric referral. Of the sample, 87% were untreated while only 13% received antidepressants. Tricyclics, which are lethal in overdose, were the drugs of choice. None of the sample was treated with the safer specific serotonin reuptake inhibitors (SSRIs). Females were 3 times as likely to be treated as were males, and those seeing psychiatrists were 4 times more likely to be treated with antidepressants than those seeing general practitioners (GPs). The physically ill were rarely treated.

Conclusions:

These findings suggest that early geropsychiatric assessment and vigorous treatment could prevent many suicides in old age.

(Can J Psychiatry 1996;41:217-222)

Key Words:

suicide, geriatric, diagnoses, depression, treatment, antidepressants, physical illness, referral, stigma


Occurrence and Effects of Personality Disorders in Depression: Are They the Same in the Old and Young?

M Oluwafemi Agbayewa, MB

Objectives:

To determine the frequency and effects of personality disorders on episodes of depression in elderly and young inpatients. Personality disorders are common and may affect the prognosis of Axis I disorders.

Methods:

Clinical records of 89 elderly inpatients and a matched comparison group of 119 young inpatients were reviewed to confirm the diagnosis of a major depressive episode according to the DSM-III-R criteria. The frequency of personality disorder diagnoses in the 2 groups was determined. Within each group, severity, functioning, and treatment were compared between those with and without personality disorders.

Results:

Personality disorders were diagnosed more frequently in the young (40.3%) than in the elderly (27%). Both rates were similar to previous reports. Cluster C disorders were the most common personality disorders found in the elderly, compared to cluster B disorders in the young. Personality disorder in the young was associated with longer episodes of depression (P = 0.035) and poorer family relations (P < 0.001); whereas in the elderly, personality disorder was associated with more severe episodes (P = 0.014).

Conclusions:

These findings suggest that the frequency and effects of personality disorders on the depressed patient may differ according to age.

(Can J Psychiatry 1996;41:223-226)

Key Words:

personality disorders, depression, hospitalized, old age, young, comparison


From Evidence to Conclusions in Psychiatric Research

Dan Bilsker, PhD

Objective:

To identify problems in the derivation of conclusions from evidence in psychiatry research.

Method:

The scientific model of falsificationism is described as determining the logical requirements for proving conclusions from research evidence. Common types of problematic conclusions are identified, and examples from the current research literature are given.

Results:

Poorly formed conclusions are based on inadequate hypotheses, ambiguously phrased, blind to negative findings, fallacious in logic, or neglectful of alternative explanations.

Conclusions:

The risks of accepting poorly formed conclusions are premature closure of scientific investigations, poor basis for decisions in psychiatric practice, and provision of misinformation to patients. It is recommended that practitioners be attentive to this aspect of critically appraising research.

(Can J Psychiatry 1996;41:227-232)

Key Words:

critical appraisal, evidence-based, conclusions


A Review of the Psychobiology and Pharmacotherapy of Posttraumatic Stress Disorder

Laurence Katz BA, MD, William Fleisher MD, FRCPC, Kevin Kjernisted MD, FRCPC, Paul Milanese MD, FRCPC

Objective:

To review the literature on certain psychobiologic elements of posttraumatic stress disorder (PTSD) as they pertain to possible pharmacotherapeutic interventions.

Method:

The literature pertaining to the neuroanatomical, neurochemical, and cellular elements was reviewed. As well, both controlled and uncontrolled studies of pharmacotherapy in PTSD were analyzed.

Results:

The literature suggests that the stress response triggers certain neuromodulators with subsequent psychoneurological restructuring; that various antidepressants have been demonstrated to be effective for treatment of criterion B symptoms; that, to date, a single antidepressant has been demonstrated to be effective in a controlled trial for criterion C symptoms; and that, to date, in controlled trials, antidepressants and a benzodiazepine have proved effective for criterion D symptoms.

Conclusion:

Currently, a comprehensive approach requires multimodel understanding and multimodal treatment.

(Can J Psychiatry 1996;41:233-238)

Key Words:

posttraumatic stress disorder, psychobiology, pharmacotherapy


A Double-Blind, Multicentre Study of Paroxetine and Maprotiline in Major Depression

Ulrich Schnyder, MD, Annemarie Koller-Leiser, BPharm

Objective:

This study was performed to compare the clinical efficacy, side effects, and safety of paroxetine and maprotiline, the latter being the most frequently prescribed antidepressant in Switzerland.

Method:

Seventy-one patients (in and outpatients) with major depression were randomly allocated to treatment with paroxetine (20 to 40 mg daily) or with maprotiline (50 to 150 mg daily). Efficacy was measured by means of the Hamilton Psychiatric Rating Scale for Depression, the Montgomery-Asberg Depression Rating Scale, the Clinical Global Impression, and the Hopkins Symptom Checklist.

Results:

The 2 components showed a similar efficacy. The adverse effect profile was comparable in the 2 treatment groups, although the findings showed a nonsignificant trend pointing in the direction of lower side effects with paroxetine.

Conclusion:

In the moderate dose regimens tested, the 2 components seemed to be of similar efficacy, with comparable profiles of side effects and safety.

(Can J Psychiatry 1996;41:239-244)

Key Words:

antidepressants, serotonin reuptake inhibitors, paroxetine, maprotiline, major depression, clinical efficacy, side effects, safety


Syndrome de Capgras : Perspectives ouvertes par la neuropsychologie cognitive

Jacques B Debruille, MD, PhD and Emmanuel Stip, MD, MSc, CSPQ

Objective:

To examine the way in which certain concepts regarding the physiopathology of Capgras' syndrome (1) have been tested neuropsychologically.

Methods:

Data consist of approximately 30 studies selected for their relevance to the cerebral stages of face processing in patients with schizophrenia, patients with Capgras' syndrome and normal subjects.

Results:

Study of this work shows: a) that with respect to patients, authors have focused on the stage of treatment corresponding to the facial recognition phase per se; b) but that it is also possible to study the phase corresponding to knowledge and beliefs relative to individuals and to evaluate the existence of the cleavage proposed by numerous psychodynamicians.

Conclusions:

Views from the field of neuropsychology, like those from the field of psychodynamics, can therefore be tested. By offering a means of developing testable predictions in experimental protocols, cognitive neuro- psychology methods will, in short, make it possible to reject erroneous concepts and demonstrate accurate ones. Limited here to the example of Capgras' syndrome, we advocate that the same methods be applied to Capgras' syndrome as to each symptom of schizophrenia.

(Can J Psychiatry 1996;41:245-250)