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Editorial
The Role of Pharmaceutical Companies in Research and Development — Plaudits and Cautions
Quentin Rae-Grant
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Guest Editorial
Diagnostic Concepts and the Prevention of Schizophrenia
Ming T Tsuang, Stephen V Faraone
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In Review
Understanding Predisposition to Schizophrenia: Toward Intervention and Prevention
Ming T Tsuang, William S Stone, Stephen V Faraone
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Preventing Schizophrenia and Psychotic Behaviour: Definitions and Methodological Issues
Stephen V Faraone, Hendricks Brown, Stephen J Glatt, Ming T Tsuang

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Original Research
Association of QEEG Findings With Clinical Characteristics of OCD: Evidence of Left Frontotemporal Dysfunction

Ôenel Tot, Aynur Özge, Ülkü Çömelekolu, Kemal Yazici, Nilgün Bal

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Ecstasy and Drug Consumption Patterns: A Canadian Rave Population Study
Samantha R Gross, Sean P Barrett, John S Shestowsky, Robert O Pihl

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Research Methods in Psychiatry
The 2 “Es” of Research: Efficacy and Effectiveness Trials

David L Streiner,

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Brief Communication
Serum Cholesterol Level Comparison: Control Subjects, Anxiety Disorder Patients, and Obsessive–Compulsive Disorder Patients

Helmut Peter, Iver Hand, Fritz Hohagen, Anne Koenig, Olaf Mindermann, Frank Oeder, Markus Wittich

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Perceptions of Intimidation in the Psychiatric Educational Environment in Edmonton, Alberta
Phil Tibbo, CJ de Gara, Treena M Blake, Carolyn Steinberg, Brian Stonehocker

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Senior Residents in Psychiatry: Views on Training in Developmental Disabilities
Philip Burge, Hélène Ouellette-Kuntz, Bruce McCreary, Elspeth Bradley, Pierre Leichner

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Evidence That Latitude is Directly Related to Variation in Suicide Rates
George E Davis, Walter E Lowell

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CPA Position Paper
The 1996 CMA Code of Ethics Annotated for Psychiatrists

 


Book Reviews
(PDF)
Substance Abuse Treatment and the Stages of Change: Selecting and Planning Interventions.

Handbook of Personality Disorders: Theory, Research and Treatment

A Clinical Guide to Sleep Disorders in Children and Adolescents

Love Relations: Normality and Pathology

The Mental Health Matrix: A Manual to Improve Services


Letters to the Editor
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Massive Weight Gain and Hostility Force Mirtazapine Stoppage

Functional Dyspepsia and Mirtazapine

Re: Using Language in Psychiatry

Dr Fine Replies

Psychotic Mania in Bipolar II Depression Related to Sertraline Discontinuation

Délirium associé à l’azithromycine

Behavioural Therapy for the Treatment of Alcohol Abuse and Dependence

Book Review

Personality Disorders

Handbook of Personality Disorders: Theory, Research and Treatment. W John Livesley, editor. New York: Guilford Press; 2001. 626 p. US$65.00.


Reviewer rating*: Excellent

Review by Paul S Links, MD, FRCPC
Toronto, Ontario

This book was conceived to provide an “in-depth survey and appraisal” of our current state of knowledge about personality disorders. A handbook, thus named, indicates that the essence of a field is found between the covers; it should be a resource for both the novice and the expert. In this volume, John Livesley has masterfully achieved this goal. He has probably created the reference text for the study of personality disorders and, as well, an editorial role that may extend through a series of future editions. Livesley’s success is not surprising. He is already the editor of the Journal of Personality Disorders, professor and former head of the Department of Psychiatry, University of British Columbia, and an internationally recognized researcher in the field. Livesley has assembled an extensive array of academic expertise that includes leaders in developmental psychology, behavioural genetics, psychometrics, neurobiology, cognitive psychology, psychopharmacology, and psychoanalysis. The internationally recognized experts contributing to this volume include Lorna Smith Benjamin, Emil Coccaro, Glen Gabbard, John Gunderson, Marsha Linehan, Theodore Millon, Tracie Shea, and Thomas Widiger.

The book is organized into 5 parts: Part I, “Theoretical and Nosological Issues”; Part II, “Etiology and Development”; Part III, “Diagnosis and Assessment”; Part IV, “Treatment”; and Part V, “Treatment Modalities and Special Issues.” Given the scope of this volume, it is important to acknowledge certain topics that have not been included. Livesley explains that theoretical positions such as classic psychoanalysis, objects relations theory, and self-psychology have been purposely omitted because there is a lack of systematic empirical research in these areas. The book is not organized to discuss specific DSM-IV diagnostic entities, primarily because Livesley strongly asserts that “current classifications are arbitrary and temporary systems that have heuristic value in stimulating and guiding research and in organizing clinical observations, rather than definitive statements of the way that personality pathology should be organized” (p x).

Part I, “Theoretical and Nosological Issues,” begins with an introductory chapter in which Livesley challenges current concepts used to define and classify personality and personality disorders. Traditionally, “temperament” has been defined as the biological substrate of personality, whereas character has been defined as traits and behaviours that are environmentally determined. Livesley notes, however, that all personality traits appear to be heritable, and this distinction is therefore flawed. The categorical approach to classification is carefully dismantled in favour of a dimensional approach. According to Livesley, “Problems such as overlap, high usage of personality disorders not otherwise specified diagnosis, low reliability, and limited evidence of validity can be attributed to failure to adopt a dimensional model” (p 18). Livesley’s own research suggests that personality phenotypes are made up of a large number of genetic building blocks, rather than a few overarching traits. Therefore, the complexity of personality likely arises from the multiple ways these blocks may be combined—a model that discounts the possibility of discrete categories of personality disorder.

In the third chapter of Part I, Thomas Widiger provides an enlightening review of the history of the official classification systems and their attempts to deal with personality disorders. Although Widiger remains critical of current DSM approaches, he acknowledges that criticizing our current systems has become “a rite of passage for any leading investigators today” (p 77). He discusses the issues that must be addressed in the development of the ICD-11 and the DSM-V. One of the major challenges outlined by Widiger is to set diagnostic thresholds for personality disorders, whether a categorical or a dimensional method of classification is adopted. Widiger acknowledges that this issue will only be resolved by reliably defining what is meant by clinically significant impairment resulting from personality disorders. As yet, little research exists to explain the relation between social and occupational dysfunction and personality pathology.

Regina Dolan-Sewell, Robert Krueger, and Tracie Shea present an excellent review of the literature examining the co-occurrence of Axis I and Axis II disorders. They purposely avoid the use of the term “comorbidity,” preferring instead the term “co-occurrence,” because “comorbidity” traditionally refers to 2 or more “distinct” disorders existing together. They indicate that “our understanding of mental disorders has not yet reached the level at which current nosological entities can be described as truly ‘distinct’” (p 85). The authors conclude that having an Axis II disorder increases the patient’s risk for being diagnosed with an Axis I disorder. They observe that the strongest relations exist between substance abuse disorders and Cluster B personality disorders, and between somatoform disorders and Cluster C personality disorders. There is little evidence for other specific relations between Axis I and Axis II disorders.

Part II, “Etiology and Development,” addresses several areas of inquiry that are seldom mentioned when discussing personality disorders. Kim Bartholomew, Marilyn Kwong, and Stephen Hart offer an excellent overview of attachment theory and the connections between attachment problems and personality disorders. Although there is no simple alignment of attachment pathology and specific personality disorders, attachment theory provides an exciting and rather new conceptual model that may enhance the targeting of therapies, the prediction of initiation and completion of therapy, and the evaluation of outcomes of certain intervention strategies. A seldom-discussed issue in psychiatry is the question, Can personality change? Jennifer Tickle and colleagues comprehensively address this question in Chapter 11. They review the basic arguments regarding the nature of personality—whether “personality” refers to objective and observable traits; whether it refers to holistic attributes including roles, attitudes, goals, and behavioural tendencies; or whether, according to the perspective of the situationalists, personality is inseparable from social context.

Part III, “Diagnosis and Assessment,” has only 2 chapters but demonstrates how relevant this work is to both researchers and practitioners. Lee Anna Clark and Julie Harrison thoroughly review all the instruments that assess personality disorders and discuss both trait-based and diagnostically based self-report and interview measures. In the second chapter of Part III, Roy MacKenzie discusses the application of structured assessment measures to the clinical care of patients with personality disorders. For example, he proposes using symptom questionnaires to monitor the course of psychotherapy much as you might monitor the course of antidepressant medication therapy. The psychotherapy literature suggests that a sense of well-being emerges early in therapy, followed by symptom reduction and, later, by interpersonal and social change. Assessment measures allow clinicians and patients to monitor the course of psychotherapy response objectively. Mac-Kenzie discusses the value of sharing questionnaire results with patients and gives specific examples of the merit of the feedback.

As with any large, edited volume, the chapter quality varies, although the range is not dramatic. Two of the most disappointing chapters are found in Part IV, “Treatment.” The chapter by William Piper and Anthony Joyce gives an overview of psychosocial treatments for personality disorders and reviews the literature targeting specific problem behaviours and personality disorder–specific approaches. Yet, under problematic behaviours, there is no mention of alcohol or substance abuse. Indeed, the topic of alcohol or drug abuse does not even appear in the subject index. This is the book’s only major omission, especially considering that the book has been targeted toward practising clinicians. This chapter is also missing some key references. For example, the discussion of borderline personality disorder (BPD) does not include the recent randomized controlled trail by Bateman and Fonagy (1,2). Although residential and milieu approaches to the management of BPD are included, assertive community treatment of patients with this disorder is not even mentioned. Paul Markovitz’s chapter on pharmacotherapy is also incomplete and his conclusions idiosyncratic. For example, key references related to lithium and valproate therapy in patients with BPD are missing. In his review, Markovitz concludes that neuroleptics are not indicated for controlling aggression, impulsivity, anxiety, and suicidality. This conclusion is contrary to the consensus opinion of the working group on BPD that recently developed treatment practice guidelines. This group’s published algorithm for the treatment of impulsive-behavioural symptoms in BPD includes low-dose neuroleptics as the second line of intervention after selective serotonergic reuptake inhibitor (SSRI) antidepressants (3). However, the section on treatment does include some unique chapters. Anthony Ryle reviews the cognitive-analytic therapies for personality disorders, a model that has attracted more interest in Europe than in North America. Chapter 22 provides a rare overview of psychoeducational approaches to managing personality disorders. These approaches have reinforced the appropriateness of psychiatric rehabilitation models for the care of patients with severe personality pathology. Two promising models are discussed. The McLean Psychoeducational and Multiple Family Group developed by John Gunderson and colleagues is adapted from the programs developed for the families of patients with schizophrenia. As well, Perry Hoffman and others have developed a family program based on dialectical behaviour therapy.

Part V, “Treatment Modalities and Special Issues,” indicates the breadth of this volume. This section includes an extensive review of group therapy, proceeding from general principles to specific studies and along the way raising many questions for future examination. Hassan Azim reviews the use of partial hospitalization for patients with personality disorders. Stephen Hart discusses the forensic issues related to these patients, yet makes the discussion relevant to general practitioners. Livesley concludes with a presentation of his framework for the integrated approach to the treatment of patients with personality disorders.

This book is very reasonably priced, given that it has more than 600 pages. Although it pays attention to the latest research in each area covered, the text is overall clear and understandable for practising psychiatrists. The book is well laid out, includes both an author and subject index, and is essentially free of production errors.

In summary, the Handbook of Personality Disorders is a magnificent achievement. This book is an important resource, and a space should be made for it on the shelf of any individual studying or treating individuals with personality disorders.

References

1. Bateman AW, Fonagy P. Effectiveness of partial hospitalization in the treatment of borderline personality disorder: a randomized controlled trial. Am J Psychiatry 1999;156:1563–9.

2. Bateman AW, Fonagy P. Treatment of borderline personality disorder with psychoanalytically oriented partial hospitalization: an 18-month follow-up. Am J Psychiatry 2001;158:36–42.

3. American Psychiatric Association. Practice guidelines for the treatment of patients with borderline personality disorder. Washington (DC): American Psychiatric Publishing Inc; 2001.



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