Canadian Psychiatric Association

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Editorial
Geriatric Psychiatry: Complex Challenges, Promising Treatments
Kenneth I Shulman
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In Review
Cognitive Pharmacotherapy of Alzheimer’s Disease and Other Dementias
Nathan Herrmann

(PDF)

Brief Screening Tests for Dementia
Wendy J Lorentz, James M Scanlan, Soo Borson

(PDF)

Effective Use of Electroconvulsive Therapy in Late-Life Depression
Alastair J Flint, Nadine Gagnon

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Review Papers
Are Leptin and Cytokines Involved in Body Weight Gain During Treatment With Antipsychotic Drugs?

Trino Baptista, Serge Beaulieu

(PDF)

Original Research
Strategies of Collaboration Between General Practitioners and Psychiatrists: A Survey of Practitioners’ Opinions and Characteristics

Ricardo J M Lucena, Alain Lesage, Robert Élie, Yves Lamontagne, Marc Corbière

(PDF)

A Test of the Phase Model of Psychotherapy Change
Anthony S Joyce, John Ogrodniczuk, William E Piper, Mary McCallum

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Brief Communication
Lamotrigine Use in Geriatric Patients With Bipolar Depression

Matthew Robillard, David K Conn

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Dissolution Profile, Tolerability, and Acceptability of the Orally Disintegrating Olanzapine Tablet in Patients With Schizophrenia
Pierre Chue, Barry Jones, Cindy C Taylor, Ruth Dickson

(PDF)

Progress Against Major Depression in Canada
Scott B Patten MD

(PDF)


Book Reviews
(PDF)

Obsessive–Compulsive Disorder: A Practical Guide
Reviewed by
Arun V. Ravindran

We Fly, We Cry: Our Lives With Manic Depression
Reviewed by
Paul Grof

Geriatric Consultation Liaison Psychiatry
Reviewed by
Ron Keren

Psychotherapy With Children and Adolescents
Reviewed by
Allan Frankland

The Early Stages of Schizophrenia
Reviewed by
Mary V. Seeman



Letters to the Editor
(PDF)

Re: Atypical Antipsychotic Use in Treating Adolescents and Young Adults With Developmental Disabilities

Reply: Atypical Antipsychotic Use in Treating Adolescents and Young Adults With Developmental Disabilities

Evidence Supports Validity of Seasonal Affective Disorder

Reply: Evidence Supports Validity of Seasonal Affective Disorder

Seasonal Affective Disorder: The Latitude Hypothesis Revisited

Treatment Of Posttraumatic Stress Disorder With Tiagabine

Assessing Pain Tolerance in a Patient With Acute Psychosis

Musical Hallucinations During a Treatment With Benzodiazepine

Bupropion-Methylphenidate Combination and Grand Mal Seizures

The Association of Depressed Affect and Stroke in Institutionalized Canadians

Quetiapine and Neuroleptic Malignant Syndrome

Letters to the Editor

The Association of Depressed Affect and Stroke in Institutionalized Canadians

Dear Editor:

Depression following stroke is common, with a reported prevalence ranging between 25% and 46% (1). Depression may adversely affect functioning, recovery, and survival and may increase the risk of stroke morbidity and mortality.

The Canadian National Population Health Survey (NPHS) has 2 components: a household component and an institutional component. A previous analysis of stroke data from the NPHS was based exclusively on the household component, and the number of subjects reporting stroke and depression was too low to support a statistical analysis (2).  Statistics Canada has now released the data for the institutional component, and it is now possible to evaluate the association between stroke and depression in a national sample of institutionalized adults.

The target population for the 1996–1997 NPHS institution survey included all long-term residents of health institutions in Canada, excluding the territories, Indian reserves, and Canadian Forces bases (3). Data collection was carried out by personal interview, where possible, or by proxy interview, when required because of illness or incapacity (59.1% of interviews were completed by proxy). The sample consisted of 2118 individuals representing a target population estimated at 222 967. The institutional response rate for this survey was 100% (n = 213), and the individual response rate was 88.9%. We used a single item to evaluate depression: “How would you describe yourself as being usually?” Subjects who responded “unhappy, with little interest in life” and “so unhappy that life is not worthwhile” were regarded as suffering from depression. The survey interview also included a question asking, “Do you suffer from the effects of a stroke, such as paralysis or speech problems diagnosed by a health professional?” Finally, an item asked whether the subject had been diagnosed with a mental disorder by a health professional. Statistical analysis employed procedures recommended by Statistics Canada to account for the survey sampling procedures.

Very substantial proportions in this population reported depression and stroke: 16.1% and 20.1%, respectively. Depression was approximately twice as common in those with stroke (22.7%; 95%CI, 21.5% to 23.9%) as in those without stroke (12.8%; 95%CI, 10.9% to 14.6%). The association was equally evident in men and women and persisted after stratification for age (that is, over or under age 70 years).

The major weakness of the NPHS institution depression data is the measurement of mood status, which is based on a single self-report item. To address this, we identified the subset of those subjects reporting depression who also reported having had a mental disorder diagnosed by a health professional; 5.4% of persons with stroke fell into this category (95%CI, 3.5% to 7.3%), compared with 2.9% of those not reporting the effects of a stroke (95%CI, 2.1% to 3.7%). The rates are much different, but the approximate doubling of prevalence is still evident.

This analysis confirms, as expected, that stroke is strongly associated with depression in residents of health care institutions in Canada.

References

1. Robinson RG. Prevalence of depressive disorder In: Robinson RG, editor. The clinical neuropsychiatry of stroke. Cambridge (UK): Cambridge University Press; 1998. p 53–9.

2. Hodgson C. Prevalence and disabilities of community-living seniors who report the effects of stroke. CMAJ 1998;159 (6 Suppl):S9–S14.

3. Statistics Canada, Health Statistics Division. National population health survey 1996–1997. Health institutions, public use microdata file documentation. Ottawa: Minister of Supply and Services; 1999.

SB Patten, MD, PhD
R Ramasubbu, MD, Msc
JSA Simpson, PhD, MD
Calgary, Alberta




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