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Editorial
Mood Disorders—New Definitions, New Treament Directions
Paul Grof
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In Review
"Cade's Disease" and Beyond: Misdiagnosis, Antidepressant Use, and a Proposed Definition for Bipolar Spectrum Disorder
S Nassir Ghaemi, James Y Ko, Frederick K Goodwin
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The Neurobiology of Bipolar Disorder: Focus on Signal Transduction Pathways and the Regulation of Gene Expression
Yarema Bezchlibnyk, L Trevor Young

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Original Research
Major Depression and Its Association With Long-Term Medical Conditions

Lisa M Gagnon, Scott B Patten

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Seasonal Affective Disorders: Relevance of Icelandic and Icelandic-Canadian Evidence to Etiologic Hypotheses
Jóhann Axelsson, Jón G Stefànsson, Andrés Magnússon, Helgi Sigvaldason, Mikael M Karlsson

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Canadian Psychiatric Inpatient Religious Commitment: An Association With Mental Health
Marilyn Baetz, David B Larson, Gene Marcoux, Rudy Bowen, Ron Griffin

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The Moderating Effects of Coping Strategies on Major Depression in the General Population
JianLi Wang, Scott B Patten

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Antidepressant Side Effects in Depression Patients Treated in A Naturalistic Setting: A Study of Bupropion, Moclobemide, Paroxetine, Sertraline, and Venlafaxine
JD Vanderkooy, Sidney H Kennedy, R Michael Bagby

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Treatment Delays for Involuntary Psychiatric Patients Associated With Reviews of Treatment Capacity
Michelle Kelly, Sandra Dunbar, John E Gray, Richard L O'Reilly

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Book Reviews
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Books Received

Letters to the Editor
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The Neurobiology of Bipolar Disorder: Focus on Signal Transduction Pathways and the Regulation of Gene Expression



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Manuscript received and accepted February 2002.

1PhD Candidate, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario.
2Professor and Vice Chair of Research, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario.
Address for correspondence: Dr LT Young, McMaster University, Department of Psychiatry and Behavioural Neurosciences, HSC–4N77A, 1200 Main St West, Hamilton, ON L8N 3Z5
e-mail: youngt@mcmaster.ca