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Guest Editorial
Psychiatric Epidemiology: Vibrant Art and Penetrating Science
Elliot M Goldner
(PDF)


In Review
The National Survey of Mental Health and Well-Being in Australia: Impact on Policy
Scott Henderson

(PDF)

Child Psychiatric Epidemiology and Canadian Public Policy-Making: The State of the Science and the Art of the Possible
Charlotte Waddell, David R Offord, Cody A Shepherd, Josephine M Hua, Kimberley McEwan

(PDF)


Review Papers
Prevalence and Incidence Studies of Schizophrenic Disorders: A Systematic Review of the Literature

Elliot M Goldner, Lorena Hsu, Paul Waraich, Julian M Somers

(PDF)


Original Research
Sleep Quality in Chronic Pain Patients

Kemal Sayar, Meltem Arikan, Tulin Yontem

(PDF)

Psychiatric Disorders and Use of Mental Health Services by Ontario Women
Sarah Frise, Allan Steingart, Margaret Sloan, Michelle Cotterchio, Nancy Kreiger

(PDF)

Counsellors in Primary Care: Benefits and Lessons Learned
Nick Kates, Anne-Marie Crustolo, Sheryl Farrar, Lambrina Nikolaou

(PDF)

Neuropsychological Performance in DSM-IV ADHD Subtypes: An Exploratory Study With Untreated Adolescents
Marcelo Schmitz, Luciana Cadore, Marcelo Paczko, Letícia Kipper, Márcia Chaves, Luis A Rohde, Clarissa Moura, Márcia Knijnik

(PDF)


Brief Communication
Benefits of Switching From Typical to Atypical Antipsychotic Medications: A Longitudinal Study in a Community-Based Setting

Peter E Cook, Joel O Goldberg, Ryan J Van Lieshout

(PDF)

Homicide in the Canadian Prairies: Elderly and Nonelderly Killings
AG Ahmed, Robin PD Menzies

(PDF)


Book Reviews
(PDF)

History of Psychiatry
Reviewed by
Sean P Beingessner

General Psychiatry
Reviewed by
Michael F Myers

Chronic Fatigue Syndrome
Reviewed by
Ellie Stein

Geriatric Psychiatry
Reviewed by
Matt Robillard

Psychiatrie générale
Reviewed by
Pierre Doucet



Letters to the Editor
(PDF)

Categorizing Continuous Variables

A Case of Neuroleptic Malignant Syndrome With Clozapine and Risperidone

Zonisamide Treatment of Bipolar Disorder: A Case Report

Combined Use of Atypical Antipsychotics and Cognitive-Behavioural Therapy in Schizophrenia

Distress Levels in Patients With Premenstrual Dysphoric Disorder

Alcoholism, Seasonal Depression, and Suicidal Behaviour

Recruiting Residents Through a Summer Medical Student Program

A Case of Paroxetine-Induced Galactorrhea

Beyond Principal-Component Analysis of the Positive and Negative Syndrome Scale in Patients With Schizophrenia

Olanzapine-Induced Hair Loss

Paternal Age as a Risk Factor

In Review

Child Psychiatric Epidemiology and Canadian Public Policy-Making:
The State of the Science and the Art of the Possible

Charlotte Waddell, MSc, MD, CCFP, FRCPC1, David R Offord, MD, FRCPC2, Cody A Shepherd, BA (Hon)3, Josephine M Hua, BSc4, Kimberley McEwan, MSc, PhD, RPsych5,

 

Epidemiological studies have characterized the high burden of suffering that child psychiatric disorders cause—14% of children (1.1 million in Canada) have clinically important disorders at any given time. In this review, we summarize the recent research and discuss several unresolved scientific issues that must be addressed to make epidemiology more useful to policy-makers. We then discuss implications for policy-making to improve children’s mental health outcomes. Overall, given the high prevalence rates, increasing clinical services alone will not suffice; rather, a multifaceted mix of strategies is required.

(Can J Psychiatry 2002; 47:825–832)

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Clinical Implications

  • Child psychiatric disorders cause a high burden of suffering.

  • Increasing clinical services alone will not reduce the burden of suffering.

  • Epidemiology can assist policy-makers to plan a mix of programs and services.

Limitations

  • Several methodological issues need to be resolved in the research.

  • More studies are needed on causal factors and patterns of service use.

  • Research–policy links need improvement.


Key Words
: child psychiatry, epidemiology, public policy

Résumé : L’épidémiologie de la pédopsychiatrie et l’élaboration des politiques canadiennes : l’état de la science et l’art du possible

“Politics is the art of the possible.” Bismarck (1)

Epidemiology—the study of the distribution and determinants of health and illness in human populations—plays a crucial role in characterizing the burden of suffering associated with any health problem, including child psychiatric disorders (2). Good-quality epidemiological information is essential for developing sound public policies to improve children’s mental health (3). In general, the intended outcomes of children’s mental health policies are optimal development and well-being for all children, a reduction in the impairments associated with mental disorders, and the effective and efficient use of public funds toward these ends (4–6). Good quality epidemiological information can assist policy-makers in achieving each of these outcomes. In particular, the following kinds of information are important for policy-making: data on prevalence to estimate needs, data on causal risk and protective factors to inform the design of effective prevention and treatment programs, and data on patterns of service use to monitor outcomes (4).

Several challenges complicate policy-making in children’s mental health. Development is an overarching issue that must always be considered in planning any programs or services for children (7). Moreover, because children develop in close interaction with their environment, their needs cannot be considered separately from conditions at home, at school, and in the community (8). Children’s mental health policies must therefore take both development and broader perspectives on the determinants of health into account (9,10). In addition, children’s services are typically provided by a diverse array of sectors, including health, education, social services, and (sometimes) child protection and justice services. This situation requires significant coordination among the multiple sectors involved (5,6). These challenges make it even more crucial for policy-makers in children’s mental health to have access to good-quality epidemiological information to guide planning.

Public policy-making is inherently complex, occurring in a crucible of competing ideas, interests, and institutional structures, where scientific information such as that derived from epidemiology is only one of many influences (11). Children’s mental health must compete with other health care needs, as well as with a myriad of other issues facing legislative and administrative policy-makers, issues such as education, the environment, fiscal restraint, and even road repair. The “art of the possible” for policy-makers concerned with children’s mental health often involves making trade-offs in dynamic, contentious, and nonrational environments.

This review examines how child psychiatric epidemiology can be more useful to policy-makers who craft the art of the possible in the complex context of children’s mental health. First, we summarize recent child psychiatric epidemiological research that pertains to Canadian public policy- making. While not all research should have eventual practical applications, the need for sound public policy poses an increasing challenge to the scientific community with respect to the relevance of research topics, methods, and findings. Consequently, we also discuss the state of the science and the issues that need to be resolved to make the research more useful to policy-makers. Finally, we comment on implications for policy-making.

Review of the Research

Background
The burden of suffering for any health problem may be characterized by its frequency, morbidity, and associated human and fiscal costs (12). According to these criteria, child psychiatric disorders cause a large burden of suffering. In terms of frequency, studies over the past 20 years have suggested that, at any given time, approximately 20% of children may have significant mental disorders (3,13,14). When present, these disorders permeate every aspect of development and functioning at home, at school, and in the community (6). Many childhood disorders also persist, affecting eventual adult productivity and functioning (7). The associated human and fiscal costs are enormous, arguably making psychiatric disorders the leading children’s health problem today (5,6).

While previous studies have covered a wide range of populations and problems, they have not always focused on issues directly pertinent to Canadian children. For this reason, we undertook a review of the recent child psychiatric epidemiological research with a specific focus on relevance for Canadian public policy-making.

Methodology
We used the following approach to select studies for review:  original articles published in English over the past 20 years were initially identified using Medline. We used the following search terms: mental disorders, epidemiology, prevalence, and child (age 0 to 18 years). Reference lists in recent key review articles (3,7,13,14) were also searched by hand.

We wanted to focus on studies that were large-scale, rigorously designed, and reasonably comprehensive in terms of ages and disorders assessed. Further, we wanted to focus on studies conducted in populations that were comparable with Canadian children. Consequently, the following criteria were used to select studies for more detailed review: studies had to assess representative community samples of at least 1000 children from Canada, the US, Great Britain, Australia, or New Zealand. In addition, studies had to include both children and adolescents and both boys and girls. They had to employ standardized assessment protocols for evaluating clinically important symptoms based on the DSM (III, or later editions, or equivalent) (15). To further ensure that only clinically important disorders were included, studies had to specifically assess impairment. They also had to incorporate reports from multiple informants, such as children, parents, and teachers. Studies had to report overall prevalence rates and rates for 2 or more disorders. Finally, they had to examine associated factors, patterns of service use, or both.

A total of 1263 relevant publications were initially identified using Medline. Most large-scale studies were described in several different publications. As a result, publications were grouped according to study and then assessed by the first and third authors. We identified 15 unique studies as being likely to meet criteria (13 from Medline and 2 from the hand search). Of these 15 studies, 6 met criteria for inclusion in our review. Final decisions about which studies to include were reached by consensus among the first, second, and third authors.

Summary of Findings
The following 6 studies met criteria for inclusion in our review: the Ontario Child Health Study (OCHS) (16–19), the NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study (20–22), the Great Smoky Mountains Study (GSMS) (23–26), the Virginia Twin Study of Adolescent Behavioural Development (VTSABD) (27), the Quebec Child Mental Health Survey (QCMHS) (28), and the British Child Mental Health Survey (BCMHS) (29–32). We were unable to include a recent Australian study—the Child and Adolescent Component of the National Survey of Mental Health and Well-being (33)—which would have met criteria if impairment had been assessed.

Table 1 summarizes study characteristics, methodology, and overall prevalence rates for all 6 studies. Table 2 provides  disorder-specific prevalence rates. Table 3 summarizes associated factors. Table 4 presents patterns of service use.

Some key findings emerged with respect to the prevalence of children’s mental disorders, associated factors, and patterns of service use. Table 1 shows that the overall community prevalence rates for clinically important mental disorders (based on assessment of both symptoms and impairment) ranged from 10%  to 20%. This table also reveals the considerable heterogeneity among studies regarding sample size, age of children, basic methodology, and time frame.

Table 2 shows that the estimated overall prevalence rate for all disorders was 14%, which translates into approximately 1.1 million Canadian children who may be affected. Table 2 also outlines estimated disorder-specific prevalence rates compiled from all 6 studies. Anxiety, attention, conduct, and depressive disorders were the most common.

Two studies also reported overall comorbidity rates and found that 47% to 68% of children with mental disorders had 2 or more disorders (18,27). In addition, OCHS found that children with mental disorders also experienced more chronic physical health and school problems (18).

All studies except MECA reported on factors that were significantly associated with increased prevalence of mental disorders in children, as shown in Table 3. With respect to sex, boys are at greater risk for mental disorders. Age, however, is also a factor: risks for boys are greater when they are younger, while risks for girls are greater when they are older. There were many disorder-specific rate variations; nevertheless, these data suggest that interactions may exist between age and sex, affecting prevalence of mental disorders. Significant differences in prevalence rates were not found between urban and rural populations in 3 of the 4 studies that measured this variable. However, low family income was associated with significantly higher rates of mental disorder in all 3 studies that measured this variable. Only 2 studies looked at ethnic groups, and no differences were found. Although association does not imply causation, determining associated factors is an important first step in identifying causal risk and protective factors (2). These reports on factors associated with increased prevalence of mental disorders provideb useful leads for further prospective research to establish which factors may be causal and thus worth targeting in children’s mental health prevention and treatment programs.

Table 1 Child psychiatric epidemiological study characteristics

 

Studies reviewed

Characteristic

OCHS

MECA

GSMS

VTSABD

QCMHS

BCMHS

Survey location

Ontario, Canada

Connecticut, Georgia, New York, Puerto Rico, US

North Carolina, US

Virginia, US

Quebec, Canada

England, Scotland, and Wales

Sampled population

All children living in a household

All children living in a household in 8 urban counties

All children attending public school in 11 rural counties

All families with twins

All children living in a household

All children living in a household

Excluded from sample

Residence on a First Nations reserve or in an institution

Primary language other than English or Spanish

First Nations children (surveyed separately)

Ethnicity other than “white”

Mental or sensory disabilities, residence on a First Nations reserve or in a remote area

No postal code for household address

Sample size

2679

1285

1015

2762

2004

10 438

Age of subjects

4–16 years

9–17 years

9, 11, 13 years

8–16 years

6–14 years

5–15 years

Follow-up

After 4 years

Longitudinal cohort study

Longitudinal cohort study

na

After 18 months

Diagnostic criteria

DSM-III

DSM-III-R

DSM-III-R

DSM-III-R

DSM-III-R

DSM-IV, ICD-10

Assessment of symptoms

Scales based on CBCL

DISC

CAPA

CAPA

DISC, Dominic

DAWBA, SDQ

Assessment of impairment

Rutter severity criteria

DISC, CGAS

CAPA, CGAS, CAFAS, SIS

CAPA

DISC

DAWBA, SDQ

Informants

Children (12–16 years), parents,

teachers

Children, parents

Children, parents

Children, parents, teachers

Children, parents, teachers (6–11 years)

Children (11–16 years), parents, teachers

Definition of “caseness”

Clinician judgement, child, parent, or teacher report

Computer algorithms, child or parent report

Computer algorithms, child or parent report

Computer algorithms, child or parent report

Prevalence rates reported separately by informant

Computer-
assisted clinician ratings of all reports

Time frame (months)

6

6

3

3

6

6

Overall prevalence (%)

18.1

12.8

20.3

14.2

12.7

9.5

CBCL = Child Behaviour Checklist;
DISC = Diagnostic Interview Schedule for Children;
CAPA = Child and Adolescent Psychiatric Assessment;
DAWBA = Development and Well-Being Assessment;
SDQ = Strengths and Difficulties Questionnaire;
CGAS = Children’s Global Assessment Scale;
CAFAS = Child and Adolescent Functional Assessment Scale;
SIS = Social Interactions Survey

OCHS = Ontario Child Health Study;
MECA = National Institute of Mental Health Methods for the Epidemiology of Child and Adolescent Mental Disorders Study;
GSMS = Great Smoky Mountains Study;
VTSABD = Virginia Twin Study of Adolescent Behavioral Development;
QCMHS = Quebec Child Mental Health Survey;
BCMHS = British Child Mental Health Survey



Table 2 Prevalence of children’s mental disorders

Disorder

Prevalence (%)

Estimated prevalence (%)c

95% CIc

Approximate number in Canadad

OCHS

MECAa

GSMS

VTSABD

QCMHSb

BCMHS

 

Any anxiety disorder

9.6

5.7

7.0

3.8

6.4

4.2-9.2

507 000

ADHDe

6.1

3.3

1.9

1.4

5.4

1.4

4.8

2.7-7.3

380 000

Conduct disorder

5.4

3.2

3.3

4.3

1.0

2.4

4.2

2.4-6.5

333 000

Any depressive disorder

4.5

1.5

1.2

2.5

0.9

3.5

1.0-7.1

277 000

Substance abuse

1.4

0.1

0.8

0.5-1.3

63 000

PDDe, f

0.3

0.3

24 000

OCDe

0.2

0.2

0.2

0.1-0.3

16 000

Any eating disorder

0.1

0.1

0.1

0.1-0.2

8 000

Tourette syndrome

0.1

0.1

0.1

0.1-0.2

8 000

Schizophreniaf

0.1

0.1

8 000

Bipolar disorderf

< 0.1

< 0.1

< 8 000

Any disorderg

18.1

12.8

20.3

14.2

12.7

9.5

14.3

11.4-17.6

1 134 000

aSymptoms and “moderate” impairment

bMean of separate rates reported by children, parents (incorporating impairment), and teachers (where available)

cBayesian approach used to pool prevalence rates and account for sample size (34); rates from 3 or more studies pooled using a flat prior and a random-effects model, in the expectation of significant heterogeneity in sample size, age, methodology, and time frame; otherwise, rates pooled using a flat prior and a fixed-effects model

dEstimated prevalence multiplied by 2001 Canadian census figure of 7 927 000 children aged 0 to 19 years (35)

eADHD = attention-deficit hyperactivity disorder; PDD = pervasive developmental disorder; OCD = obsessive-compulsive disorder

fEstimated prevalence and approximate number in Canada based on rates from a single study

gMay include disorders other than those listed above



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